In general, females and older males have less water in their organs than younger males. This means less alcohol enters their organs and more alcohol stays in their bloodstream. Younger females make less of the stomach enzyme that breaks down alcohol in the stomach. This means more alcohol is available to be soaked up into the blood. So they will have a higher blood alcohol level than a male of the same age who drinks the same amount of alcohol. Talk to your doctor if you have questions about how your body breaks down alcohol.
Heredity may play a role in how alcohol and your body act together. Moderate drinkers who have genes that cause a slower breakdown of alcohol are at much lower risk for heart and blood vessel disease than moderate drinkers who have genes that cause rapid breakdown of alcohol.
Alcohol is broken down more slowly when it's soaked up. The process of soaking up alcohol is slowed when you drink alcohol during or right after a meal. The slower soaking up process lets the liver break down alcohol at a rate that keeps more of it from reaching other organs.
Because the liver breaks down alcohol, people with liver disease are more sensitive to drinking. Some medicines may cause harmful reactions if you drink while taking them. Alcohol affects the breakdown of many medicines by increasing the activity of some and decreasing the activity of others. For example, heavy alcohol consumption when taking acetaminophen can lead to liver damage.
The danger of drinking is much higher than the possible heart and blood vessel benefits for people with a history of alcoholism.